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Inhibition of Runx by Ro5-3335 Affects Nematostella Regeneration
Full text linkThis undergraduate research project is being made available in KU ScholarWorks with the permission of the author. The project was supervised by Dr. Paulyn Cartwright, associate professor of Ecology and Evolutionary Biology at the University of Kansas.The sea anemone, Nematostella vectensis, has the ability to fully regenerate amputated body parts. We hypothesize that Runx, a transcription factor, controls the cellular processes for regeneration, specifically the transition between cellular proliferation and cellular differentiation. A known inhibitor to the Runx pathway is Ro5-3335, a benzodiazepine. Inhibiting the Runx pathway by Ro5-3335 will help determine if Runx is necessary for proper regeneration in Nematostella. We introduced bisected Nematostella polyps to Ro5-3335 for a 24-48 period and observed regeneration of oral ends. Tentacle regeneration appeared delayed in treated polyps compared to the controls. It was not until three weeks post-treatment that the treated animals recovered normal regeneration. We conclude that Ro5-3335 appears to repress regeneration in the polyps which suggests that the Runx pathway is important for proper regeneration in Nematostella
Block Card 3335 Glenwood Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: box bay | Dwelling | 3335 Glenwood Avenue (Toledo, Ohio) | Cushing Place Addition (Toledo, Ohio) | Folk House Styl
Block Card 3335 Monroe Street
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Chicago School | 3335 Monroe Street (Toledo, Ohio) | commercial buildings | W.P. Anderson Company Addition | Auburndale Area (Toledo, Ohio
Block Card 3335 Detroit Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Curved bay | Dwelling | 3335 Detroit Avenue (Toledo, Ohio) | Old West End Area (Toledo, Ohio) | Cushing Place Addition (Toledo, Ohio) | Folk House Styl
Block Card 3335 Aldringham Road
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Saltbox houses | Dwelling | 3335 Aldringham Road (Toledo, Ohio) | Extension of Forest View Addition (Toledo, Ohio) | Deveaux Area (Toledo, Ohio) | West Toledo (Toledo, Ohio
IO Islamic 3335. Akbarnâma, History of the Emperor Akbar
No full textIO Islamic 3335. Akbarnâma, History of the Emperor Akbar</p
Block Card 3335 Bishop Street
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Cleveland double | 3335 Bishop Street (Toledo, Ohio) | duplex | W.P. Anderson and Company Addition | Auburndale Area (Toledo, Ohio
Block Card 3335 Parkwood Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Bungalow Style | Dwelling | 3335 Parkwood Avenue (Toledo, Ohio) | Old West End (Toledo, Ohio) | Corydon Heights Addition (Toledo, Ohio
Berg-Kerzen, Bergische Kerzenfabrik Burscheid bei Cöln, A. Braun & Co Karlsruhe, Musterschutz No. 3335
No full textBERG-KERZEN, BERGISCHE KERZENFABRIK BURSCHEID BEI CÖLN, A. BRAUN & CO KARLSRUHE, MUSTERSCHUTZ NO. 3335
Berg-Kerzen, Bergische Kerzenfabrik Burscheid bei Cöln, A. Braun & Co Karlsruhe, Musterschutz No. 3335 ( -
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