1,725,471 research outputs found

    Resumen ejecutivo de los documentos ALADI/SEC/di 3073 y 3074

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    Secretaría General de la ALADI.Informe mensual sobre el comportamiento del gasto presupuestal para el período enero-noviembre 2022 (ALADI/SEC/di 3073) -- Informe sobre la situación financiera de la Asociación al 30 de noviembre de 2022 (ALADI/SEC/di 3074)

    Gender Difference in Retirement Income and Pension Policy – Simulating the Effects of Various DB and DC Schemes. ENEPRI Research Reports No. 59, 25 August 2008

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    This analysis evaluates the relative pension positions of men and women, under different characterisations of their respective working lives and pension designs. Both Defined Benefit (DB) and Defined Contribution (DC) schemes are considered, as well as a few variants of their basic pension formula, each exemplifying a stylised normative framework. Not surprisingly, the working career is the most relevant factor in determining the relative retirement income of women with respect to men; pension systems can compensate, but only up to a point. As for a comparison between DB and DC systems, taken without explicit redistributive measures, the latter can fare better than the former in providing a more equal distribution of retirement income between men and women, because it removes the greater return to steeper earnings profiles, more characteristic of men. The introduction of a minimum pension provision in the DB system improves the relative position of women with discontinuous or poor careers, while, in DC systems, a formal recognition of women’s care activities through pension credits seems less effective than neutralising their longer life expectancy in the determination of the pension benefits using unisex longevity tables

    Supplementary Material for: Aberrant Placental Villus Expression of miR-486-3p and miR-3074-5p in Recurrent Miscarriage Patients and Uterine Expression of These MicroRNAs during Early Pregnancy in Mice

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    MicroRNAs (miRNAs) are critical regulators of gene expression; they have emerged as new players in the pathophysiology of reproductive disorders such as preeclampsia and recurrent miscarriage (RM). In this study, miRNA expression profiles were determined by deep sequencing analysis in placental villi obtained from women with RM and with gestational age-matched normal pregnancy (NP). A total of 69 miRNAs were found to be aberrantly expressed in RM. Five of these human (Homo sapiens) miRNAs (hsa-miRNAs), including hsa-miR-3074-5p, -486-3p, -1269b, -6765-3p and -144-3p, were validated by qRT-PCR in 12 RM and 10 NP placental villi. Hsa-miR-3074-5p expression was significantly higher, while hsa-miR-486-3p expression was significantly lower, in RM compared to NP. Subsequently, the expression of mouse (Mus musculus) miR-486-3p (mmu-miR-486-3p) and mmu-miR-3074-5p, which are identical to hsa-miR-486-3p and hsa-miR-3074-5p, respectively, were examined by qRT-PCR in the uterus during early pregnancy. Mmu-miR-486-3p expression was significantly increased during the peri-implantation period, and the levels were significantly higher at implantation than at non-implantation sites. In contrast, the expression of mmu-miR-3074-5p was markedly decreased at implantation compared to non-implantation sites. These data suggest that miR-486-3p and miR-3074-5p may be involved in embryo implantation and that their aberrant expression is associated with RM. Larger studies are warranted to follow up this pilot study

    UMNH:Mamm:3074

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    UMNH:Mamm:3074 Voucher specimen study ski

    Supplemental Material, Suppl_Table_1_Differentially_expressed_genes - miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro

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    Supplemental Material, Suppl_Table_1_Differentially_expressed_genes for miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro by Yan Gu, Yan Shi, Qian Yang, Wen-Wen Gu, Ya-Ping He, Hua-Jun Zheng, Xuan Zhang, Jian-Mei Wang, and Jian Wang in Reproductive Sciences</p

    Supplemental Material, Supplementary_Figures_revision_2017-6-6 - miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro

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    Supplemental Material, Supplementary_Figures_revision_2017-6-6 for miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro by Yan Gu, Yan Shi, Qian Yang, Wen-Wen Gu, Ya-Ping He, Hua-Jun Zheng, Xuan Zhang, Jian-Mei Wang, and Jian Wang in Reproductive Sciences</p

    Astronomische Nachrichten, nos 3074-3077

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    R. R. Astronomische Nachrichten, nos 3074-3077. In: Bulletin astronomique, tome 9, 1892. pp. 130-136

    Supplemental Material, Suppl_Table_3_Interaction_analysis_of_up-regulated_genes - miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro

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    Supplemental Material, Suppl_Table_3_Interaction_analysis_of_up-regulated_genes for miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro by Yan Gu, Yan Shi, Qian Yang, Wen-Wen Gu, Ya-Ping He, Hua-Jun Zheng, Xuan Zhang, Jian-Mei Wang, and Jian Wang in Reproductive Sciences</p

    Supplemental Material, Suppl_Table_2_Interaction_analysis_of_down-regulated_genes - miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro

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    Supplemental Material, Suppl_Table_2_Interaction_analysis_of_down-regulated_genes for miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extravillous Trophoblast–Derived HTR8/SVneo Cells In Vitro by Yan Gu, Yan Shi, Qian Yang, Wen-Wen Gu, Ya-Ping He, Hua-Jun Zheng, Xuan Zhang, Jian-Mei Wang, and Jian Wang in Reproductive Sciences</p

    sj-docx-1-tej-10.1177_20417314231184512 – Supplemental material for Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9

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    Supplemental material, sj-docx-1-tej-10.1177_20417314231184512 for Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9 by Tao Jiang, Shenghong Miao, Jingjie Shen, Wenjing Song, Shenglong Tan and Dandan Ma in Journal of Tissue Engineering</p
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