1,880,300 research outputs found
I-205 Toll Project environmental assessment. Vietnamese
No full textBộ Giao thông Vận tải Oregon (ODOT) đang đề xuất thực hiện thu phí trên Cầu Abernethy và Cầu Sông Tualatin trên Xa lộ Liên tiểu bang 205 (I-205) để tăng doanh thu cho việc xây dựng các cải tiến theo kế hoạch đối với I-205, bao gồm nâng cấp và mở rộng địa chấn, và để quản lý sự tắc nghẽn. Đánh giá Môi trường này, do ODOT hợp tác với Cục Quản lý Đường cao tốc Liên bang phát triển, trình bày đánh giá về tác động của phí cầu đường và các cải tiến I-205 được tài trợ bởi phí cầu đường đối với môi trường tự nhiên và con người theo Đạo luật Chính sách Môi trường Quốc gia.Environmental Assessment -- Appendix A. I-205 Toll Project Comparison of Screening Alternatives -- Appendix A. I-205 Toll Project Comparison of Screening Alternatives Addendum -- Appendix B. I-205 Toll Project Performance Measures -- Appendix C. I-205 Toll Project Transportation Technical Report -- Appendix C. I-205 Toll Project Transportation TR Modeling Memo -- Appendix C1. I-205 Toll Project Mitigation Workshop Summaries -- Appendix C2. I-205 Toll Project Truck Toll Multiplier Sensitivity Analysis - Transportation Effects -- Appendix D. I-205 Toll Project Air Quality Technical Report -- Appendix D1. I-205 Toll Project Criteria Pollutant Emissions Memorandum -- Appendix D2. I-205 Toll Project Truck Toll Multiplier Sensitivity Analysis - Air Quality Effects -- Appendix E. I-205 Toll Project Energy and Greenhouse Gas Technical Report -- Appendix E1. I-205 Toll Project Truck Toll Multiplier Sensitivity Analysis - Energy and Greenhouse Gases -- Appendix F. I-205 Toll Project Economics Technical Report -- Appendix F1. I-205 Toll Project Truck Toll Multiplier Sensitivity Analysis - Economic Effects -- Appendix G. I-205 Toll Project Noise Technical Report -- Appendix H. I-205 Toll Project Abbreviated Visual Impact Assessment -- Appendix H. I-205 Toll Project AVIA Attachment B Design Guidelines -- Appendix I. I-205 Toll Project Social Resources and Communities Technical Report -- Appendix J. I-205 Toll Project Environmental Justice Technical Report -- Appendix K. I-205 Toll Project Land Use Technical Memorandum -- Appendix L. I-205 Toll Project Geology and Soils Technical Memorandum -- Appendix M. I-205 Toll Project Hazardous Materials Technical Memorandum -- Appendix N. I-205 Toll Project Historic and Archaeological Resources Technical Memorandum -- Appendix N. I-205 Toll Project Historic and Archaeological Resources Memorandum Attachment A -- Appendix N. I-205 Toll Project Historic and Archaeological Resources Memorandum Attachment B -- Appendix O. I-205 Toll Project Vegetation and Wildlife Technical Memorandum -- Appendix P. I-205 Toll Project Wetlands and Water Resources Technical Memorandum -- Appendix Q. I-205 Toll Project Cumulative Impacts Technical Report -- Appendix R. I-205 Toll Project Engagement Summary."Mã khóa ODOT: 21371."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in Vietnamese
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
Full text linkBackground: Esophageal squamous cell carcinoma (ESCC) is often diagnosed at later stages until they are incurable. MicroRNA (miR) is a small, non-coding RNA that negatively regulates gene expression mainly via translational repression. Accumulating evidence indicates that deregulation of miR is associated with human malignancies including ESCC. The aim of this study was to identify miR that could be specifically expressed and exert distinct biological actions in ESCC. Methods: Total RNA was extracted from ESCC cell lines, OE21 and TE10, and a non-malignant human esophageal squamous cell line, Het-1A, and subjected to microarray analysis. Expression levels of miR that showed significant differences between the 2 ESCC and Het-1A cells based on the comprehensive analysis were analyzed by the quantitative reverse transcriptase (RT)-PCR method. Then, functional analyses, including cellular proliferation, apoptosis and Matrigel invasion and the wound healing assay, for the specific miR were conducted. Using ESCC tumor samples and paired surrounding non-cancerous tissue obtained endoscopically, the association with histopathological differentiation was examined with quantitative RT-PCR. Results: Based on the miR microarray analysis, there were 14 miRs that showed significant differences (more than 2-fold) in expression between the 2 ESCC cells and non-malignant Het-1A. Among the significantly altered miRs, miR-205 expression levels were exclusively higher in 5 ESCC cell lines examined than any other types of malignant cell lines and Het-1A. Thus, miR-205 could be a specific miR in ESCC. Modulation of miR-205 expression by transfection with its precursor or anti-miR-205 inhibitor did not affect ESCC cell proliferation and apoptosis, but miR-205 was found to be involved in cell invasion and migration. Western blot revealed that knockdown of miR-205 expression in ESCC cells substantially enhanced expression of zinc finger E-box binding homeobox 2, accompanied by reduction of E-cadherin, a regulator of epithelial mesenchymal transition. The miR-205 expression levels were not associated with histological differentiation of human ESCC. Conclusions: These results imply that miR-205 is an ESCC-specific miR that exerts tumor-suppressive activities with EMT inhibition by targeting ZEB2.Kayoko Matsushima... Gregory J Goodall... et al
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORDO
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORPD
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
C-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIOR
No full textC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORC-205 APLICÓ IPN EXAMEN COMPLEMENTARIO PARA INGRESO A NIVEL SUPERIORjp
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