1,759,226 research outputs found

    Etching of Nathaniel Fiennes (1607/8–1669)

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    Etching of Nathaniel Fiennes (1607/8–1669) by Wenceslaus Hollar. Titled 'W. Hollar fecit Londini. Ao. 1644'

    Nobiliss. Virginis Annæ Mariæ A Schurman, Opuscula Hebræa, Græca, Latina, Gallica : Prosaica & metrica /

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    Anna Maria Van Schurman (1607-1678) is perhaps the only female author in the Elzeviers' catalogue. She was born in Germany, but moved to Utrecht in the Netherlands at a young age. As a child genius, she could already read at the age of 4. In her teenage years, she excelled in Latin and other subjects, as well as traditionally female pastimes, such as paper cutting, painting, and embroidery. At a time when women were not allowed into higher education, she became the first female student in the Netherlands at Utrecht University from 1636. This book is a collection of her poetry in various languages, as well as her Latin- and French-language letters to respected scholars of her time, demonstrating her important position in seventeenth century intellectual life."First published by Abraham and Bonaventura Elzevier in 1648. Republished by Elsevier B.V. in 2014."Anna Maria Van Schurman (1607-1678) is perhaps the only female author in the Elzeviers' catalogue. She was born in Germany, but moved to Utrecht in the Netherlands at a young age. As a child genius, she could already read at the age of 4. In her teenage years, she excelled in Latin and other subjects, as well as traditionally female pastimes, such as paper cutting, painting, and embroidery. At a time when women were not allowed into higher education, she became the first female student in the Netherlands at Utrecht University from 1636. This book is a collection of her poetry in various languages, as well as her Latin- and French-language letters to respected scholars of her time, demonstrating her important position in seventeenth century intellectual life.Elsevie

    Auto del Nacimiento, de Gaspar de Mesa, autógrafo e inédito (1607)

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    Édition et étude de l’Auto del nacimiento de Gaspar de Mesa, pièce inédite et autographe, datée de 1607 et signée par son auteur, avec le texte des avis des censeurs et de l’approbation donnés à Madrid la même année. Pièce écrite en vers, elle met en drame le récit évangélique de la naissance du Christ avec une finalité festive et catéchistique.Edition and study of the Auto del nacimiento [nativity play] by Gaspar de Mesa, an unpublished handwritten work dated 1607 and signed by its author, which received censures as well as approval in Madrid, 1607. Written in verse, it dramatizes the New Testament story of the birth of Christ with a celebratory and catechetical aim.Edición y estudio del Auto del nacimiento de Gaspar de Mesa, pieza inédita, autógrafa, datada en 1607 y firmada por su autor, con censuras y aprobación en Madrid, 1607. Escrita en verso, dramatiza el relato neotestamentario del nacimiento de Cristo, con finalidad celebrativa y catequizadora

    Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy

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    Neurofibrillary tangles (NFTs) are associated with neuronal loss and correlate with cognitive impairment in Alzheimer disease, but how NFTs relate to neuronal death is not clear. We studied cell death in Tg4510 mice that reversibly express P301L mutant human tau and accumulate NFTs using in vivo multiphoton imaging of neurofibrillary pathology, propidium iodide (PI) incorporation into cells, caspase activation, and DNA labeling. We first observed that in live mice, a minority of neurons were labeled with the caspase probe or with PI fluorescence. These markers of cell stress were localized in the same cells and appeared specifically within NFT-bearing neurons. Contrary to expectations, the PI-stained neurons did not die during a day of observation; the presence of Hoechst-positive nuclei in them on the subsequent day indicated that the NFT-associated membrane disruption, as suggested by PI staining, and caspase activation do not lead to immediate death of neurons in this tauopathy model. This unique combination of in vivo multiphoton imaging with markers of cell death and pathological alteration is a powerful tool for investigating neuronal damage associated with neurofibrillary pathology

    IX A 1 - Alte Stadtrechnungen (1606 - 1607)

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    IX A 1 - ALTE STADTRECHNUNGEN (1606 - 1607) IX A 1 - Alte Stadtrechnungen (1606 - 1607) ( -

    IX A 1 - Alte Stadtrechnungen (1607 - 1608)

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    IX A 1 - ALTE STADTRECHNUNGEN (1607 - 1608) IX A 1 - Alte Stadtrechnungen (1607 - 1608) ( -

    IX A 1 - Alte Stadtrechnungen (1607 - 1608)

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    IX A 1 - ALTE STADTRECHNUNGEN (1607 - 1608) IX A 1 - Alte Stadtrechnungen (1607 - 1608) ( -

    IX A 1 - Alte Stadtrechnungen (1606 - 1607)

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    IX A 1 - ALTE STADTRECHNUNGEN (1606 - 1607) IX A 1 - Alte Stadtrechnungen (1606 - 1607) ( -

    Επικτητου Ενχειριδιον (VD16 E 1607)

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    ΕΠΙΚΤΗΤΟΥ ΕΝΧΕΙΡΙΔΙΟΝ (VD16 E 1607) Επικτητου Ενχειριδιον (VD16 E 1607) ( - ) Cover ( - ) Title page (1) ANGELI POLITIANI IN EPICTETI STOICI ENchiridon, è Græco à se interpretatum, ad Laurentium Medicem epistolat. (41) EPICTET STOICI ENCHIRIDION. (45
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