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Collation Model for Ms. Codex 58: Theologia naturalis.
Full text linkLatin translation of a Spanish theological and philosophical work attempting to reconcile the natural and supernatural orders of truth, in opposition to the distinction previously made by the Scholastics. The text that appears in printed versions begins after the end of a fairly lengthy prologue (p. 3).https://repository.upenn.edu/sims_models/1158/thumbnail.jp
Collation Model for Ms. Codex 1070: Genelogies of the Erles of Lecestre and Chester [manuscript].
Full text linkGenealogy of Robert Dudley, Earl of Leicester, tracing his descent from the earls of Leicester and Chester, beginning with individuals of the 11th and 12th centuries, and providing the heraldic devices of the principal members of these families. Although the genealogy may have been compiled in association with Robert Dudley\u27s appointment as lieutenant of the Order of the Garter in 1572 or the birth of his illegitimate son in 1574, Robert Dudley is mentioned in the introduction and is represented by the final coat of arms (f. 17v), although the lack of his name among those of his siblings is noted in a late 16th- or early 17th-century hand (f. 18r).https://repository.upenn.edu/sims_models/1162/thumbnail.jp
Purinergic Signaling in Painful Pulpitis
No full textInjury of the tooth pulp is often excruciatingly painful and yet the receptors and neural circuit mechanisms that transmit this form of pain remain poorly defined in both clinical human and preclinical rodent models. The role of purinergic pathways are of particular interest and potential relevance in dental inflammation and pain. This study examined the involvement of purinergic receptors in human dental inflammatory pain by comparing their distribution in healthy pulps compared to symptomatic and asymptomatic inflamed pulps, and then testing for sex differences in expression. Ionotropic P2X2R and P2X3R were selected for their implication in pain; whereas ecto-nucleotidase NTPDase1 (CD39) reflects extracellular ATP concentration. We found P2X3R and P2X2R, as well as CD39, to colocalize with protein gene product 9.5 (PGP9.5)-positive nerves in control tissues. P2X3R was additionally found on odontoblasts, and CD39 on other non-neuronal structures. Both immunohistochemistry and immunoblots demonstrated that all three proteins were significantly increased in symptomatic pulpitis, suggesting both receptors and agonist ATP were elevated with increased pain. Increased expression of P2X3 and CD39 were more frequently observed in women than men. Our findings support a role for increased purinergic signaling in humans with inflammatory dental pain, with preference in women. This differential response suggests purinergic signaling may contribute to sex differences in pain. To further study signaling pathways of painful pulpitis in the preclinical model, quantifiable behavioral models, namely the Mouse Grimace Scale (MGS) and Facial von Frey assay, were evaluated for their validity in assessing dental pulp pain in mice. We found that unilateral pulp exposure injury to the first maxillary molar in mice resulted in significant increase in MGS from 24 h onward, indicating presence of spontaneous pain. Mechanical allodynia, assessed by the Facial von Frey assay, progressed more gradually with significant increases on both sides of the face on day 4, and unwillingness to tolerate filaments above 0.6 g by day 6 post-injury. This work demonstrates that we have clear, easily identifiable behavioral readouts for trigeminal nociception in the mouse following dental injury
BRING IT ON HOME: A Decolonial Analysis of Musical Instruments in the Penn Museum
Full text linkIn conversations focused on decolonizing institutional spaces like ethnographic museums, repatriation remains a contentious goal. Whether museums are willing to change their ethics and practices to relinquish these spoils is one issue, but poor documentation continues to severely hinder efforts of returning objects to source communities. As such, this project reflects on musical instruments in ethnographic archives and their unique representations of cultural heritage, using an ‘ukulele (29-58-122) from the Penn Museum’s collections as a case study. Investigating the provenance of this instrument and connecting it with the cultural significance of its construction (design, use, etc.) will create valuable discussions of cultural heritage and the disembodiment of objects from ancestral homes. This research interacts with literature on decoloniality and musical repatriation to understand how musical instruments convey cultural heritage. Imagining how instruments might be used as symbols of identity in the hands of their descendants is critical to connecting music with cultural repatriation. The ongoing work of musical repatriation in museum contexts should rethink how these objects are cared for, recognizing them beyond artifacts. By taking insight from musicians or other specialists, museums can begin to treat instruments as objects that “breathe” and allow them to keep producing culture
Lesker PVD75 E-beam/Thermal Evaporator (PVD-02) Standard Operating Procedure
Full text linkStandard Operating Procedure for the Lesker PVD75 E-beam/Thermal Evaporator (PVD-02) located at the Quattrone Nanofabrication Facility within the Singh Center for Nanotechnology at the University of Pennsylvaniahttps://repository.upenn.edu/scn_sop/1027/thumbnail.jp
Ms. Codex 1640 - Manipulus florum peritorum. Video Facsimile
No full texthttps://repository.upenn.edu/sims_video/1202/thumbnail.jp
Penn Library\u27s LJS 467 - Hādhā min Khawāṣs al-manāzil wa-hiya fī ... (Video Orientation)
No full texthttps://repository.upenn.edu/sims_video/1205/thumbnail.jp
Heidelberg DWL66+ Laser Writer (LW-01) Standard Operating Procedure
Full text linkStandard operating procedure (SOP) for Heidelberg DWL66+ laser writer
How Would 401(k) ‘Rothification’ Alter Saving, Retirement Security, and Inequality?
Full text linkThe US has long incentivized retirement saving in 401(k) and similar retirement accounts by permitting workers to defer taxes on contributions, levying them instead when retirees withdraw funds in retirement. This paper develops a dynamic life cycle model to show how and whether ‘Rothification’ – that is, taxing 401(k) contributions rather than payouts – would alter household saving, investment, and Social Security claiming patterns. We show that these changes differ importantly for low- versus higher-paid workers. We conclude that moving to a system that taxes pension contributions instead of withdrawals will lead to later retirement ages, particularly for the better-educated. It also would reduce work hours and lifetime tax payments and increase wealth and consumption inequality. In addition, we show how these behaviors would differ in a persistently low interest rate environment versus a more “normal” historical return world
Penn Library\u27s Library\u27s LJS 486 - Kitāb Alghāz fī al-lughah al-ʻArabīyah.(Video Orientation)
No full texthttps://repository.upenn.edu/sims_video/1224/thumbnail.jp