Advanced Emergency Medicine (E-Journal)
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Clinical Application Research of the Transradial Approach in Neurointerventional Surgery
Get PDFThis study aims to comprehensively investigate the clinical application and advantages of the transradial approach in neurointerventional procedures. Through in-depth analysis, it was found that the transradial approach significantly reduces the occurrence of surgical
complications, improves patient comfort, and effectively shortens hospital stays, thereby lowering overall medical costs. The study content
elaborates on the technical essentials and operational procedures of this approach in neurointerventional surgery, including preoperative
preparation, precise puncture techniques, catheter manipulation, and other critical links
Comparative analysis of visual function between Tecnis Symfony intraocular lens and monofocal aspheric intraocular lens implantation
Get PDFObjective To compare and analyze the visual function of cataract patients after Tecnis Symfony intraocular lens (IOL) and monofocal aspheric IOL implantation. Methods Fifty cataract patients admitted to our hospital from October 2023 to December 2024 were selected
and divided into experimental group (Tecnis Symfony IOL implanted，25 cases) and control group (Tecnis ZCB00 IOL implanted,25 case)
according to the type of lens implanted. Postoperative vision, adjustment range, simultaneous viewing and fusing functions, far and near stereovision, Visual function satisfaction questionnaire survey, de-lens rate, defocus curve, contrast sensitivity. Results There was no significant
difference in uncorrected visual acuity between the two groups at a distance of 5 m (P>0.05), but the visual acuity of the experimental group
at a distance of 63 cm and 30 cm was significantly better than that of the control group (P0.05), and the near stereovision of the experimental group
was better than that of the control group (P0.05). Compared with the experimental group, the number of patients with difficulty in medium and near vision was significantly higher in the control
group (P 0.05).There were
no significant differences in defocus curves and contrast sensitivity values between the two groups (P>0.05). Conclusion Tecnis Symfony
IOL can better improve most visual functions of cataract patients than Tecnis ZCB00 IOL, but some aspects of visual function improvement
still need to be optimized
A review of the research progress of organ chips in the field of biomedicine
Get PDFOrgan chips is a cutting-edge frontier science in the field of life sciences. It has broad application prospects and development space
in the fields of tissue and organ development, disease mechanism research, new drug evaluation and selection, and biological research, and it
has significant strategic significance for supporting the development of innovative drugs and translational medicine. This review summarizes the current research status, challenges, and application prospects of organ chips technology in the field of biomedicine both at home and
abroad
Clinical application analysis of neonatal swimming combined with stroking
Get PDFObjective: To investigate the effects of swimming combined with touch intervention on neonatal body weight, length, psychological development, immune response and skin health, and to provide scientific basis for clinical work. Methods: In this study, 200 newborns
were randomly divided into experimental group (swimming combined with touch intervention group) and control group (routine care group)
using a prospective randomized controlled experiment design. The experimental group swam and touched 2-3 times a week for 4 weeks; The
control group received only routine care. Before and after the intervention, weight, length, psychological development, immune response
and skin health were evaluated, and SPSS 26.0 software was used for data analysis. Result: In the experimental group, newborn body weight
increased by 1.53 kg (P < 0.001), body length increased by 2.6 cm (P < 0.05), psychological development score increased by 7.8 points (P
< 0.001), immune response increased (antibody titer increased by 18.7, P < 0.001), skin damage rate decreased (P = 0.003). There were also
significant changes in the control group. Conclusion: Swimming combined with touch intervention can significantly promote the growth and
immune function of newborns, improve their skin health, contribute to psychological development, and have high clinical application value
Importance of medicinal plants in human health
Get PDFmedicinal plants are increasingly used in aromatherapy, such as lavender essential oil for relieving stress and improving sleep, mint
essential oil for refreshing and relieving headache. Medicinal plants are not only an important guarantee for mental health, but also an important way to improve the quality of life. Medicinal plants are not only guardians of human health, but also important contributors to the earth’s ecology. In the future, with the progress of science and technology and the deepening of the concept of sustainable development, medicinal plants will play a more important role in human health and ecological protection, and make greater contributions to global health and environmental protection. Based on this, the importance of medicinal plants to human health is discussed below for reference
Progress in Research on the Antitumor Mechanisms and Clinical Applications of Active Compounds from Phellinus igniarius
Get PDFPhellinus igniarius, a medicinal fungus with significant antitumor potential, exerts its inhibitory effects through multiple mechanisms, including the induction of apoptosis and immune modulation. However, its molecular mechanisms, signaling pathways, dose-response
relationships, and the feasibility of clinical translation remain to be systematically elucidated. This essay reviews the latest research advancements in the antitumor effects of Phellinus igniarius, and identifies key challenges in areas such as synergistic effects and clinical applications. It aims to provide a reference for further research and development of Phellinus igniarius in the field of cancer therapy
Topological quantum hydrogen catalysts based on density functional theory for applications and innovations in pharmaceutical engineering
Get PDFWith the continuous progress in catalyst design, quantum catalysts have become an important direction in catalytic research, especially in hydrogen generation and pharmaceutical engineering. Density Functional Theory (DFT), as an effective quantum mechanical
computational tool, plays a crucial role in the design and optimization of catalysts. In this study, the application and innovation of topological
quantum catalysts for hydrogen generation in pharmaceutical engineering are investigated in the context of DFT theory. Topological quantum
catalysts exhibit higher catalytic activity and stability than conventional catalysts due to their special electronic structures, especially topologically protected surface states, and are particularly suitable for hydrogen generation reactions. Through DFT calculations, this study systematically analyzes the catalytic mechanism of topological quantum catalysts and evaluates their performance in the hydrogen production process.
The results show that the catalysts based on topological quantum materials have better reaction selectivity and efficiency than conventional
materials, and exhibit high greening and sustainability in pharmaceutical engineering. The innovation of this paper is that a new catalyst
design strategy is proposed, which provides an efficient and green catalytic solution for the pharmaceutical industry with a broad application
prospect
Research on Malnutrition in AIDS Patients
Get PDFMalnutrition is a major factor influencing the prognosis and quality of life of AIDS patients, and screening, assessment, diagnosis,
intervention, nutrition monitoring of patients with AIDS should be done as early as possible. AIDS patients suffer from malnutrition as a
result of impaired immune function brought on by the ongoing invasion of HIV, and malnutrition and impaired immune function are causal
of each other, affecting each other to form a vicious circle. In order to further avoid malnutrition, slow the progression of the disease, and enhance quality of life, this article examines the primary causes of malnutrition in AIDS patients as well as the nutritional programs for various
AIDS patients
Selection of tension-free herniorrhaphy for inguinal hernia in elderly patients and analysis of risk factors for postoperative chronic pain
Get PDFTo analyze the selection of tension-free herniorrhaphy and the risk factors of postoperative chronic pain in elderly patients. 100
elderly patients with inguinal hernia in our hospital from January 2024 to January 2025 were selected and randomly divided into the control
group and the observation group, with 50 cases in each group.The control group was treated with mesh-plug tension-free herniorrhaphy,
while the observation group was treated with flat tension-free herniorrhaphy, and the pain risk factors of the two groups were compared. The operation time, the first ambulation time after operation and the length of hospital stay in the observation group were higher than those in the control group (P 0.05), but the pain score of the observation group was lower than that of the control group 1 day after treatment (P < 0.05). Logistic regression analysis showed that the choice of tension-free herniorrhaphy and nerve exposure were the independent risk factors of chronic pain (P < 0.05). Tension-free repair of inguinal hernia in elderly patients should be combined with the patient’s tolerance and longterm quality of life needs, weighing the advantages of hernia ring filling and plain pain control, and choosing a reasonable operation to reduce the risk of chronic pain after operation
A Case of Acute Myocardial Infarction During Rapid Ascent to High Altitude
Get PDFMedical history: Male, 46 years old, driver. A long-term resident of the plains with no history of hypertension or altitude-related
hypertension. High-altitude BP at 110/70-120/80 mmHg, fasting blood glucose at 6.6 mmol/L (health check indicated elevated fasting blood
glucose; no further examinations conducted), previously undiagnosed diabetes, no thyroid-related disorders. Pre-altitude health assessment:
BMI: 27.27, uric acid: 446 µmol/L (2023), 457 µmol/L (2024). No smoking history; occasional alcohol consumption in small amounts (approximately 50-150 g each time, 1-2 times per month). Symptoms developed about 12 h after driving from the plains to an average altitude
of 2,580 m.Symptoms and signs: Sudden onset of squeezing pain behind the sternum after breakfast. Accompanied by palpitations, fatigue,
numbness in the fingertips, and soreness in the jaw, the patient is observed sweating profusely with a distressed expression. BP 141/89
mmHg, HR 110 beats/min, SpO2 91% (not on supplemental oxygen), R 28 breaths/min. Consciousness is clear, no cough or pink frothy
sputum, no significant respiratory distress, and no obvious abnormalities in urination or defecation. Physical examination: Bilateral pupils
are equal and round, no neck stiffness, no dry or wet rales heard in both lungs, normal muscle strength and tone in the limbs, physiological
reflexes present, and pathological reflexes not elicited. The patient developed upper back pain 0.5 h after symptom onset.Diagnostic methods:
Bedside electrocardiogram shows ST segment elevation in leads V1-V5 and frequent premature ventricular contractions (PVCs). A complete
myocardial enzyme profile, prothrombin time (PT), D-dimer, C-reactive protein (CRP), biochemical tests, chest CT, and other relevant examinations were conducted. A repeat electrocardiogram was performed.Treatment methods: Cardiac monitoring and vital sign observation were
administered, and venous access was established. Due to limitations in field medical care, percutaneous coronary intervention (PCI) could
not be performed. According to the “Guideline for rational medication of ST-segment elevation myocardial infarction in primary care,”[1] and
considering the unique circumstances of high altitude, the following treatment plan was implemented on-site: (1) Clopidogrel loading dose of
300 mg and aspirin 300 mg (chewed for rapid absorption) for antithrombotic therapy; (2) 2 million units of Urokinase dissolved in 100 ml of
normal saline (administered intravenously over 45 min) for thrombolysis (1.5 h after symptom onset). During thrombolysis, cardiac monitoring showed BP 110-140/60-86 mmHg, HR 30-80 beats/min, and R 24 breaths/min. (3) Emergency oxygen therapy. The oxygen flow rate is
set at 4 L/min via nasal cannula for continuous delivery and results in oxygen saturation levels of 95-97%.Clinical outcome: After thrombolysis, the chest pain decreased, and a repeat electrocardiogram still indicated the presence of PVCs, with ST-segment elevation reduced compared to before. Following the administration of morphine for pain relief, the patient was transferred to the Chest Pain Center at West China
Hospital, Sichuan University, approximately 4 h after symptom onset. During transport, the patient remained strictly in bed and received continuous oxygen at 2-4 L/min. Throughout the transfer, the chest pain intensity gradually reduced. Cardiac monitoring during transport showed
BP 120/60-140/89 mmHg, heart rate 50-90 beats/min, respiration rate 21-24 breaths/min, and SpO2 91%-97%; there were no instances of
urination or defecation. The patient was admitted to West China Hospital, Sichuan University, 16 h after symptom onset, and received PCI.
After one day of post-operative observation, the patient was discharged and returned home without any discomfort